When it comes to the progression seen in brain cancer, there are many different details to look into. What are the ones which seem to be the most common, you may wonder? How exactly will certain drugs be reacted to when they are implemented for the sake of helping patients in this regard? From what has been, apparently a mechanism linked to this level of growth has been seen and it has the potential to be one that can help in the various research efforts to come.
Companies such as Voices against Brain Cancer know how vital this condition is and why it is important for research to be conducted. Brain cancer will be focused on and one of the reasons for this is because of its various components, which are what play into the complex nature of various tumors. An article on Medical Xpress attested to the idea that the focus is greatly placed on glioma, which is viewed as the most aggressive type of cancer in this regard. The written report also made mention of assistance given by an FDA-approved food additive.
Medical Xpress said that the food additive in question was surveyed by University of Vermont professor Diane M. Jaworski, Ph.D., and former graduate student Patrick Long. They were able to focus onaspartoacylase, which is an enzyme that can break down a compound by the name of N-acetyl-L-aspartate. NAA is the brain's primary storage form of acetate, which is able to turn genes on or off. When it comes to the condition that is referred to as glioma, both the levels of NAA and expression of ASPA are decreased.
Even though efforts were made in order to elevate ASPA expression, the truth of the matter was that proliferation was caused, meaning that results would not be positive. However, the article said that a food additive called glyceryl triacetate could be the one to utilize for the purpose of aiding glioma patients. For those who do not know, GTA has been commonly implemented to treat Canavan disease, an inherited disorder that can cause damage to one's brain cells. Children who have this condition, as the article said, die during infancy.
With GTA put to use, though, the article detailed that the results of an experiment proved to be rather successful. Not only was GTA able to decrease the growth of glioma stem cells but it was able to do so while leaving the normal cells unharmed. This alone goes to show that there are possible results to be seen in the future, provided it is a safe compound that anyone would react positively to. With minimal toxicity and very few side-effects, this appears to be the case.
Companies such as Voices against Brain Cancer know how vital this condition is and why it is important for research to be conducted. Brain cancer will be focused on and one of the reasons for this is because of its various components, which are what play into the complex nature of various tumors. An article on Medical Xpress attested to the idea that the focus is greatly placed on glioma, which is viewed as the most aggressive type of cancer in this regard. The written report also made mention of assistance given by an FDA-approved food additive.
Medical Xpress said that the food additive in question was surveyed by University of Vermont professor Diane M. Jaworski, Ph.D., and former graduate student Patrick Long. They were able to focus onaspartoacylase, which is an enzyme that can break down a compound by the name of N-acetyl-L-aspartate. NAA is the brain's primary storage form of acetate, which is able to turn genes on or off. When it comes to the condition that is referred to as glioma, both the levels of NAA and expression of ASPA are decreased.
Even though efforts were made in order to elevate ASPA expression, the truth of the matter was that proliferation was caused, meaning that results would not be positive. However, the article said that a food additive called glyceryl triacetate could be the one to utilize for the purpose of aiding glioma patients. For those who do not know, GTA has been commonly implemented to treat Canavan disease, an inherited disorder that can cause damage to one's brain cells. Children who have this condition, as the article said, die during infancy.
With GTA put to use, though, the article detailed that the results of an experiment proved to be rather successful. Not only was GTA able to decrease the growth of glioma stem cells but it was able to do so while leaving the normal cells unharmed. This alone goes to show that there are possible results to be seen in the future, provided it is a safe compound that anyone would react positively to. With minimal toxicity and very few side-effects, this appears to be the case.
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For more details regarding brain cancer and how you can help, go to Voices against Brain Cancer.
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